Excitation/inhibition imbalance and conversion to psychosis in the clinical high risk syndrome: Biophysical modeling finds reduced pyramidal cell excitability across EEG paradigms.

Rodriguez-Sanchez J, Hauke DJ, Pinotsis D, Berndt LCS, Oloye H, Nicholas SC, Hamilton HK, Roach BJ, Bachman PM, Belger A, Carrión RE, Duncan E, Johannesen JK, Light GA, Niznikiewicz MA, Friston KJ, Addington J, Bearden CE, Cadenhead KS, Perkins DO, Walker EF, Woods SW, Cannon TD, Adams RA, Mathalon DH. Excitation/inhibition imbalance and conversion to psychosis in the clinical high risk syndrome: Biophysical modeling finds reduced pyramidal cell excitability across EEG paradigms. medRxiv. 2025 Sep 18.