Study Demonstrates 'Mismatch Negativity' as Potential Biomarker for Psychotic Disorder

A new biomarker may be on the horizon to more accurately identify psychiatric patients who may later develop fulminant psychosis, according to a study published in yesterday's Biological Psychiatry.

Daniel Mathalon, M.D., Ph.D., a professor of psychiatry at the University of California San Francisco, led a study evaluating the amount of mismatch negativity (MMN)—an auditory signaling process that travels to the frontal lobe regions in response to sound—in 101 individuals with a high clinical risk for psychosis, or schizophrenia or no history of mental illness.

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