"Clinical outcomes vary among young people exhibiting attenuated psychotic symptoms as part of the PRS," said Dr. Daniel Mathalon of the University of California, San Francisco and Dr. Holly Hamilton, who was his post-doc at the time of the study and is now on the UCSF faculty.
"About 20% progress to full-blown psychosis - most often schizophrenia - over a 2- to 3-year follow-up period, and about 30% improve and achieve remission," they told Reuters Health by email. "Current research efforts are focused on identifying biomarkers that can be used to predict the likelihood of progression to psychosis versus remission from the risk syndrome."
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